Line a 6 x 8 or 8 x 8 inch pan with parchment; set aside.
Combine all ingredients except vanilla in heavy 4-quart saucepan. Cook over medium heat, stirring occasionally until butter is melted and mixture comes to a boil, about 10-15 minutes.
Continue cooking without stirring, 25-30 minutes or until candy thermometer reaches 244°F (or to 248°F for a slightly firmer caramel) or small amount of mixture dropped into ice water forms a firm ball—see “The Cold Water Test Method” above for more detail..
Remove from heat; stir in vanilla. Pour into prepared pan. Cool slightly (so the salt doesn’t dissolve into the caramel), then sprinkle with sea salt.
When the caramel is cool, cut into pieces of your desired size.
Wrap the candies individually and store in the refrigerator. Take out to warm before serving.
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Notes
The calorie count is based on smaller (cut into 32) pieces of caramel.
I am not a health professional and nutrition data is calculated programatically. Accuracy may vary with product selection, calculator accuracy, etc. Consult a professional for the best information.